Curriculum Vitae

Family:

Wife: Deborah Ann Rice-Spellman, R.N.
Children: Wyatt, Sam, Emma, Graham

Education:

1978           West Chester State College
                   West Chester, Pennsylvania
                   B.S. Chemistry - Biology
                   Summa Cum Laude

1984           Thomas Jefferson University
                   Philadelphia, Pennsylvania
                   M.D.

1984-89     Internship and General Surgery Residency
                   Stamford Hospital
                   Stamford, Connecticut 06804

1989-92      Surgical Oncology Fellow, Department of Surgery
                   University of Chicago, Chicago, IL

Employment:

2002 -        James Spellman MD LLC
                   431 Savannah Road
                   Lewes, DE 19958
                   Surgeon/Owner

1996-02     Delaware Bay Surgical Service, P.A.
                   1539 Savannah Road
                   Lewes, DE 19958
                   Surgeon/Owner

1992-96      Roswell Park Cancer Institute
                   Department of Surgical Oncology and
                   Department of Molecular Medicine (1992-1996)
                   Buffalo, New York l4263
                   Attending Staff

1979-80     Cappel Laboratories
                   Cochranville, Pennsylvania
                   Laboratory Technician
1978-79      West Chester State College
                   West Chester, Pennsylvania
                   Teaching Assistant - Microbiology and Anatomy

Academic Appointments:

Clinical Instructor of Surgery, 1989
New York Medical College

Assistant Professor of Surgery, 1992
State University of New York at Buffalo

Board Certification:

Board Certification General Surgery, June 1990
Recertification General surgery, October 1999
Other Certification:

Advanced Trauma Life Support, 1988
Advanced Cardiac Life Support, 1983, 1996

Licensure:
Delaware
New York

Societies:

Member - Medical Society of Delaware
Member - American College of Surgeons
Member - Association for Academic Surgery
Member - The Society of Surgical Oncology
Member - American Society of Clinical Oncology
Member - American Association for the Advancement of Science
Member - American Society of Breast Surgeons

Honors and Awards:

Graduated summa cum laude, 1978
Alpha Lamda Delta Honor Society, 1978
Hobart Amory Hare Medical Honor Society, 1982
Golden Apple Teaching Award, Dept Surgical Oncology, Roswell Park Cancer Institute, 1995

Grant Support:

Core Grant Developmental Fund #CA16056      $6000
Lymphokine mRNA Expression in Breast Carcinoma and Soft Tissue Sarcoma - 1996

Teaching Activities:

Coordinator - Fellowship Journal Club/STM Service 1992-1996.
Coordinator - STM Multidisciplinary Conference 1992-1996.

Research:

NIH Research Grant with Cardeza Foundation of the Department of Hematology at Thomas Jefferson University, "Ristocetin Co-Factor Receptors on Platelets" Summer l982.Sandor Shapiro, M.D. project advisor.

Clonal Interactions and Growth Factor Expression in Squamous Cell Carcinomas - University of Chicago, 1991/Roswell Park Cancer Institute, 1992. Ralph R. Weichselbaum, M.D., project advisor, Chicago. Molly Kulesz-Martin PhD, project advisor, RPCI.
Alternatively Spliced P53 expression in human tumors - Roswell Park Cancer Institute, 1993 - 1994. Molly Kulesz-Martin PhD, project advisor.

Cytokine Patterns in Tumor Infiltrating Lymphocytes and MHC Class II Antigen Expression in Human Tumors - Roswell Park Cancer Institute, 1994- Thomas Tomasi MD PhD preceptor.

Technetium-99m Sestamibi Uptake in Melanoma and Soft-Tissue Sarcoma - Roswell Park Cancer Institute, 1993-1995. D. L. Klippenstein, S. P. Bakshi, M. A. VanSlyke and P. C. Stomper Co- Investigators.

Technetium-99m Sestamibi Uptake in Soft-Tissue Sarcoma: Kinetics and Clinical Correlation with MR Imaging and PGP Content. Roswell Park Cancer Institute, 1995-. D. Klippenstein, H. Nabi, and Y. Rustum Co- Investigators.

Publications:

Spellman J, Rogers JF, Kazarian KK: Typhlitis in Acute Leukemia, Connecticut Medicine 5l(9):565-567, l987.

Spellman J, Michelassi F: Low Anterior Resection with Coloanal Anastomosis for Rectal Carcinoma. Postgraduate General Surgery 3(2):67-70, l99l.

Spellman J: Therapy of Metastatic Melanoma with Monoclonal Antibody. New Perspectives in Cancer Diagnosis and Management l(3):7l-73,l993.

Spellman JE: Optimizing Local Control in Soft Tissue Sarcoma of the Extremity. Oncology 8(7):32-37, 1994

Spellman JE, Driscoll D, Velez A, Karakousis C: Thick cutaneous melanoma of the trunk and extremities: An Institutional review.
Surg Oncol 3:335-343, 1994.

Sticca RP, Spellman J, Perez-Mesa C, Karakousis CP: Advanced neurofibromatosis of the lower extremity requiring hemipelvectomy. Surg Rounds 18(9) :367-372, 1995

Spellman J, Kulesz-Martin M, Blumenson L, Beckett MA, Weichselbaum R: Clonal interactions in a human squamous cell carcinoma. Journal of Surgical Research 58:165-174, 1995.

Horowitz J, Spellman JE, Driscoll DL, Velez AF, Karakousis CP: Sarcomas of the large and small bowel: An Institutional review.
Journal American College of Surgeons 180: 465-471, 1995.

Spellman JE, Driscoll DL, Huben RP: Primary renal sarcoma. The American Surgeon 61: 456-459, 1995.

Velez AF, Penetrante RB, Spellman JE, Orozco A, Karakousis CP: Malignant melanoma of the gallbladder: Report of a case and review of the literature. The American Surgeon 61: 1095-1098, 1995.

Apffelstaedt JP, Driscoll DL, Spellman JE, Velez AF, Gibbs JF, Karakousis CP: Complications and outcome of external hemipelvectomy in the management of pelvic tumors. Annals of Surgical Oncology. 3: 304-309, 1996.

Karakousis CP, Velez AF, Spellman JE, Scarozza J: The technique of sentinel node biopsy. The Europ J of Surg Oncol. 22: 271-275, 1996.

North JH, Spellman JE: The role of sentinel lymph node biopsy in the management of malignant melanoma. Oncology. 10:1237-1246,1996.

North JH, Spellman JE, Velez A, Driscoll D, Kraybill WG, Petrelli NJ: Advanced squamous cell carcinoma of the skin of the trunk and extremity: Analysis of prognostic factors. J of Surg Oncol. 64: 212-217, 1997.

Loree TR, Mullins AP, Spellman JE, North JH, Hicks WL: Head and neck mucosal melanoma: A 32-year review at roswell park cancer institute. Submitted.

Spellman JE, Zhang PJ, Gollnick SO, Tomasi TB: Cytokine production by soft tissue sarcomas: Implications for immunosuppression within the tumor bed. Surgical Oncology. 5: 237-244, 1996.

Book Chapters:

Levine,E. G., Brooks, J. S. J., Spellman, J. E. and Velagapudi S.: Genitourinary Sarcomas. In: Principles and Practice of Genitourinary Oncology. Edited by D. Raghavan, H. I. Scher, S. A. Leibel and P. Lange. J. B. Lippincott Company (in press).

Spellman, J. E.: Counter-point to Chapter 13. Follow-up of the Patient with Soft Tissue Sarcoma. In: Cancer Patient Follow-up Surveillance Strategies After Primary Treatment of Cancer. Edited by F. E. Johnson and K. S. Virgo. Mosby Year Book (in press).

Spellman, J. E.: Counter-point to Chapter 14. Follow-up of the Patient with Cutaneous Melanoma. In: Cancer Patient Follow-up Surveillance Strategies After Primary Treatment of Cancer. Edited by F. E. Johnson and K. S. Virgo. Mosby Year Book (in press).

Abstracts:

Spellman JE, Beckett MA, Weichselbaum RR: Clone to Clone Interactions in a Human Squamous Cell Carcinoma. Proc Soc Surg Oncol, Los Angeles, March l8-2l, l993, pp. 23.

Spellman JE, Driscoll D, Velez A, Karakousis C: Thick cutaneous melanoma of the trunk and extremities: An institutional review. Proc Soc Surg Oncol, Houston, March l7-20, l994, pp. 59.

Apffelstaedt J, Karakousis C, Gibbs J, Spellman J, Velez A, Driscoll D: Complications and outcome of external hemipelvectomy in the management of pelvic tumors. Proc Soc Surg Oncol, Boston, March 23-26, 1995, pp. 66.

Klippenstein DL, Spellman JE, Bakshi SP, VanSlyke MA, Stomper PC: Technetium-99m Sestamibi Uptake in Melanoma and Soft-Tissue Sarcoma. Proc Am Roetgen Ray Soc, Washington, DC, April 30-May 5, 1995.

Spellman JE, Driscoll DL, Huben RP: Primary Renal Sarcoma. Proc Am Soc Clin Oncol, Los Angeles, May 20-23, 1995, pp. 544.

Spellman JE, Gollnick S, Repasky E, Tomasi T: Lymphokine mRNA Expression By Soft Tissue Sarcomas And Breast Carcinomas.
Proc Soc Surg Oncol, Atlanta, March, 1996, pp.47.

Holbrook R, Spellman JE, Velez A, Driscoll D. Karakousis C: Intermediate Thickness Cutaneous Melanoma. Proc Soc Surg Oncol, Atlanta, March, 1996, pp.53.

Karakousis C, Velez A, Spellman J, Kontzoglou K: Sentinel Node Biopsy In Malignant Melanoma. Proc Soc Surg Oncol, Atlanta, March, 1996, pp.54.

Mullins AP, Loree TR, Spellman J: Head and Neck Mucosal Melanoma: A 32-Year Review at Roswell Park Cancer Institute (RPCI). N Y Head and Neck Society, New York, May 1996, pp.

Scientific Exhibits:

Primary Extremity Adult Soft Tissue Sarcomas Karakousis CP, Velez A, Spellman JE Jr, Walsh D (Paper Session) 80th Annual Clinical Congress of American College of Surgeons October 9-14, 1994, Chicago, IL

Treatment of Sarcomas in Patients with Neurofibromatosis Velez AF, Karakousis CP, Spellman JE Jr. (Poster Presentation) 80th Annual Clinical Congress of American College of Surgeons October 9-14, 1994, Chicago, IL

Sarcomas of the Large and Small Bowel: An Institutional Review Horowitz J, Spellman JE, Driscoll DL, Velez AF, Karakousis CP. (Poster Presentation) 80th Annual Clinical Congress of American College of Surgeons October 9-14, 1994, Chicago, IL

Lymphokine mRNA Expression By Soft Tissue Sarcomas And Breast Carcinomas. Spellman JE, Gollnick S, Repasky E, Tomasi T. (Poster Presentation) 49th Cancer Symposium Soc Surg Oncol, March 21-24, 1996, Atlanta,GA.

Intermediate Thickness Cutaneous Melanoma. Holbrook R, Spellman JE, Velez A, Driscoll D. Karakousis C. (Poster Presentation) 49th Cancer Symposium Soc Surg Oncol, March 21-24, 1996, Atlanta, GA.

Sentinel Node Biopsy in Malignant Melanoma. Karakousis C, Velez A, Spellman J, Kontzoglou K. (Poster Presentation) 49th Cancer Symposium Soc Surg Oncol, March 21-24, 1996, Atlanta, GA